STYROS® HILIC (Hydrophilic Interaction Chromatography)

As Simulated Monolith™ fully uniform polymer based packings, they are intended for use in high speed, high resolution applications.
The base matrix that is fully pervious is made of highly cross linked poly (styrene-divinylbenzene).

It has a high pressure tolerance and can be used routinely up to 3,000 psi.

The goal has been to provide seamless series of stationary phases that could facilitate the transition from analytical to semi preparative and preparative applications, all within the same products and with high reproducibility.

HILIC or Hydrophilic Interaction Chromatography is a variation of normal phase chromatography with the advantage of being able to use solvents that are not miscible with water.

HILIC is also called “reverse reversed phase” or “aqueous normal phase” chromatography.
This mode of chromatography shortens the sample preparation procedures.

In the final step of the isolation of proteins whether using SPE, precipitation or liquid/liquid extraction, the isolated product is in an organic solvent. HILIC chromatography allows the direct use of them in reversed phase mode.

STYROS® HILIC are provided in two different types in order to accommodate most applications:

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